opentrons-magnetic-block
Opentrons Magnetic Block for Flex - unpowered magnetic bead separation using gripper-based labware movement with high-strength neodymium magnets for DNA/RNA purification, immunoprecipitation, and bead-based workflows
Security Assessment
About opentrons-magnetic-block
The Opentrons Magnetic Block skill provides an automated solution for unpowered magnetic bead separation, designed specifically for the Opentrons Flex robot. This skill solves the problem of manual magnetic bead separation by leveraging the gripper-based movement of labware and high-strength neodymium magnets to efficiently pull beads to the side of wells. It eliminates the need for human intervention in processes like DNA/RNA extraction, PCR cleanup, protein purification, and other bead-based workflows. The skill enhances laboratory automation, enabling faster and more reliable results in workflows that require precise and consistent bead separation.
The core feature of the Magnetic Block is its unpowered design, allowing for fully automated magnetic bead separation while offering complete control through physical plate positioning and timed delays for bead separation. The skill can be easily integrated into existing workflows, with the robot gripper managing plate movement and the user defining separation time delays. This integration is supported by Opentrons' Python-based API, making it simple to implement and control through standard scripting protocols. Importantly, the skill is specifically designed for the Opentrons Flex model, ensuring seamless compatibility with this platform.
Target users of this skill include laboratory researchers and technicians in fields such as genomics, proteomics, and biotechnology, particularly those involved in DNA/RNA purification, protein cleanup, and other bead-based separation techniques. The Magnetic Block offers a streamlined solution for automating repetitive magnetic bead separation tasks, thereby improving the efficiency, accuracy, and reproducibility of laboratory processes. The skill is also beneficial in reducing human error and freeing up valuable time for other critical laboratory tasks.
FAQ
Which robot models are compatible with the Opentrons Magnetic Block?
The Opentrons Magnetic Block is exclusively compatible with the Opentrons Flex robot. It is not compatible with the OT-2.
Do I need any special equipment to use the Magnetic Block?
Yes, the Opentrons Flex gripper is required for all plate movements with the Magnetic Block.
Can the Magnetic Block be used for heated magnetic separation?
No, the Magnetic Block does not support heated magnetic separation. It is an unpowered system that only provides magnetic separation without heating capabilities.
What labware is compatible with the Opentrons Magnetic Block?
The Magnetic Block is compatible with 96-well PCR plates that fit the magnetic footprint. Examples include `biorad_96_wellplate_200ul_pcr`, `nest_96_wellplate_100ul_pcr_full_skirt`, and `opentrons_96_wellplate_200ul_pcr_full_skirt`.
How do I load the Magnetic Block in a protocol?
You can load the Magnetic Block in a protocol using the `protocol.load_module()` function with the module name `magneticBlockV1`, specifying the location on the deck.
Install opentrons-magnetic-block
Quick Setup:
- Copy the skill folder to
.claude/skills/ - Claude will automatically detect and use the skill
Repository
jkitchin/skillz