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alphafold-database

Access AlphaFold 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.

6,195stars743forksUpdated 1/16/2026

Security Assessment

Medium Risk(60/100)

Detected risks:

Command Injection([SKILL.md] shell=True, [SKILL.md] subprocess.run)
Security Score60/100

About alphafold-database

The AlphaFold Database skill provides access to over 200 million AI-predicted protein structures, enabling researchers and developers to retrieve structural predictions with high confidence levels. This skill addresses the challenge of obtaining reliable protein structure data, significantly advancing the fields of drug discovery and structural biology. By leveraging advanced AI models developed by DeepMind and EMBL-EBI, users can access a vast repository of 3D protein structures, which are essential for various biological and pharmaceutical applications.

Key features of the AlphaFold Database skill include the ability to search and retrieve predictions based on UniProt IDs or protein names, download coordinate files in PDB/mmCIF formats, and analyze confidence metrics such as pLDDT and PAE. Users can also access bulk datasets via Google Cloud Platform, compare predicted structures with experimental data, and integrate AlphaFold predictions into their computational workflows. This makes the skill highly versatile for both academic researchers and industry professionals focused on protein engineering and drug design.

Target users for this skill include computational biologists, bioinformaticians, and pharmaceutical researchers who require accurate protein structures for their work. The skill is particularly beneficial for users involved in structure-based drug discovery, protein modeling, and those looking to enhance their research with AI-driven insights into protein structure predictions.

FAQ

How can I retrieve protein structure predictions?

You can retrieve predictions by using the Biopython library or by sending REST API requests to the AlphaFold Database.

What file formats are available for download?

Available file formats include mmCIF for model coordinates, JSON for confidence scores, and PAE matrices.

Is there a limit on the number of predictions I can access?

While there are no strict limits, accessing large bulk datasets may require proper handling and adherence to API rate limits.

Can I integrate AlphaFold predictions into my software?

Yes, AlphaFold predictions can be integrated into computational workflows and pipelines using various programming languages.

What are the system requirements for using this skill?

This skill requires Python and libraries such as Biopython for optimal functionality.

Install alphafold-database

Download and extract the skill files to your .claude/skills/ directory.

Quick Setup:

  1. Copy the skill folder to .claude/skills/
  2. Claude will automatically detect and use the skill