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neuropixels-analysis

Neuropixels neural recording analysis. Load SpikeGLX/OpenEphys data, preprocess, motion correction, Kilosort4 spike sorting, quality metrics, Allen/IBL curation, AI-assisted visual analysis, for Neuropixels 1.0/2.0 extracellular electrophysiology. Use when working with neural recordings, spike sorting, extracellular electrophysiology, or when the user mentions Neuropixels, SpikeGLX, Open Ephys, Kilosort, quality metrics, or unit curation.

17,798stars1,609forksUpdated 1/21/2026

Security Assessment

Low Risk(70/100)

Detected risks:

Secret Exposure([AI_CURATION.md] api_key=)
Security Score70/100

About neuropixels-analysis

The neuropixels-analysis skill provides a comprehensive toolkit for analyzing high-density neural recordings obtained from Neuropixels probes. It addresses the challenges associated with processing and analyzing vast amounts of neural data, specifically focusing on formats such as SpikeGLX and Open Ephys. This skill facilitates the entire workflow from raw data acquisition to the generation of publication-ready curated units, ensuring that researchers can efficiently handle complex neural datasets.

FAQ

What formats does the neuropixels-analysis skill support?

It supports SpikeGLX (.ap.bin, .lf.bin, .meta), Open Ephys (.continuous, .oebin), and NWB (.nwb) formats.

Can I use this skill for motion correction?

Yes, the skill includes functionality for detecting and correcting motion or drift in neural recordings.

What are the hardware requirements for using Kilosort4?

Kilosort4 requires a GPU for optimal performance.

Is there a way to visualize the neural recordings?

Yes, the skill includes capabilities for creating visualizations of neural data.

What preprocessing steps are recommended before spike sorting?

Recommended steps include highpass filtering, phase shift correction, bad channel detection, and common reference application.

All Files

9 files
MOTION_CORRECTION.md8.5 KB
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AUTOMATED_CURATION.md9.8 KB
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SPIKE_SORTING.md7.7 KB
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ANALYSIS.md9.6 KB
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SKILL.md11.0 KB
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AI_CURATION.md8.4 KB
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QUALITY_METRICS.md9.2 KB
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LICENSE.txt1.0 KB
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PREPROCESSING.md6.5 KB
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Install neuropixels-analysis

Download and extract the skill files to your .claude/skills/ directory.

Quick Setup:

  1. Copy the skill folder to .claude/skills/
  2. Claude will automatically detect and use the skill